Type: Dicarboxylic Acid
Name: Azelaic Acid
RDA: None Listed, (varies from person to person), 10% concentration in solution is generally sufficient, 15-20% qualifies as prescription strength
Importance- to Body:
Anti-inflammatory, Antibacterial,Treats Acne and Rosacea, Melasma
Naturally occuring Exfoliant, Anti-inflammatory, Anti-bacterial. Kills acne bacteria. Reduces inflammation clears bumps caused by rosacea, and other visible skin disorders (brown patches, post- acne blemishes), dull skin tone, signs of sensitivities
Distribution- in Body:
Skin (Surface, Uppermost layers)
Excess Effects:
Burning, Stinging, Dry Skin, Redness, Itching, Irritation, Tightness;
Excess Effects:
Dizziness, Headaches, Nausea, Contact Dermatitis, Changing of skin color
Deficiency Effects:
Food Sources:
Whole Grains such as Barley, Wheat, and Rye
Environmental/Geographic Sources:
Natural biproduct of Malassezia furfur (a yeast that lives symbiotically on human skin)
Supplemental information:
Can be found in: Topical Gels, Creams, Foams
| Names | |
|---|---|
| IUPAC name
nonanedioic acid
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| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| DrugBank | |
| ECHA InfoCard | 100.004.246 |
| KEGG | |
PubChem CID
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| UNII | |
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| Properties | |
| C9H16O4 | |
| Molar mass | 188.22 g/mol |
| Appearance | white solid |
| Density | 1.443 g/mL |
| Melting point | 109 to 111 °C (228 to 232 °F; 382 to 384 K) |
| Boiling point | 286 °C (547 °F; 559 K) at 100 mmHg |
| 2.14 g/L | |
| Acidity (pKa) | 4.550, 5.498 |
| Pharmacology | |
| D10AX03 (WHO) | |
| Topical | |
| Pharmacokinetics: | |
| Very low | |
| 12 h | |
| Legal status | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Azelaic acid is an organic compound with the formula HOOC(CH2)7COOH. This saturated dicarboxylic acid exists as a white powder. It is found in wheat, rye, and barley. It is a precursor to diverse industrial products including polymers and plasticizers, as well as being a component of a number of hair and skin conditioners.
