Methylchloroisothiazolinone

Type: Toxin
Name: Methylchloroisothiazolinone
RDA: 0
Importance- to Body:
Toxin: Lungs, Eyes, Skin
Distribution- in Body:
Skin, Respiratory System
Excess Effects:
Lung Toxicity, Allergic Reactions, Nerve Damage, Nerve Toxicity, Burns, Lung Irritation
Deficiency Effects:
None Listed
Food Sources:
None Listed
Environmental/Geographic Sources:
Liquid Cosmetics, Cleaning Products, Detergents, Lotion, Sunscreen, Liquid Soaps, Body Wash, Mascara, Shaving Cream, Shampoo, Hair Conditioner, Baby Wipes
Supplemental information:
Preservative, Anti-fungal, Antibacterial

Works Cited:
“Methylchloroisothiazolinone.” Honest Reviews of Anti-Aging Skin Care and Beauty Products, www.truthinaging.com/ingredients/methylchloroisothiazolinone.

Methylchloroisothiazolinone (Wikipedia)

Methylchloroisothiazolinone

Names
IUPAC name 5-Chloro-2-methyl-1,2-thiazol-3(2H)-one
Other names 5-Chloro-2-methylisothiazol-3(2H)-one 5-Chloro-2-methyl-4-isothiazolin-3-one Chloromethylisothiazolinone Chloromethylisothiazolone Methylchloroisothiazolinone Methylchloroisothiazolone CMI CMIT MCI MCIT
Identifiers
CAS Number	26172-55-4 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:53621 Y
ChemSpider	30800 Y
ECHA InfoCard	100.043.167
PubChem CID	33344
UNII	DEL7T5QRPN Y
InChI InChI=1S/C4H4ClNOS/c1-6-4(7)2-3(5)8-6/h2H,1H3 Y Key: DHNRXBZYEKSXIM-UHFFFAOYSA-N Y InChI=1/C4H4ClNOS/c1-6-4(7)2-3(5)8-6/h2H,1H3 Key: DHNRXBZYEKSXIM-UHFFFAOYAV
SMILES ClC=1SN(C(=O)C=1)C
Properties
Chemical formula	C4H4ClNOS
Molar mass	149.59 g·mol−1
Appearance	Colorless liquid
Density	1.02 g/cm³
Solubility in water	Miscible
Hazards
R-phrases (outdated)	R23/24/25 R34 R43 R50/53
S-phrases (outdated)	(S2) S26 S28 S36/37/39 S45 S60 S61
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is Y ?)
Infobox references

Methylchloroisothiazolinone, also referred to as MCI, is a preservative with antibacterial and antifungal effects within the group of isothiazolinones. It is effective against gram-positive and gram-negative bacteria, yeast, and fungi.

Methylchloroisothiazolinone is found in many water-based personal care products and cosmetics. Methylchloroisothiazolinone was first used in cosmetics in the 1970s. It is also used in glue production, detergents, paints, fuels, and other industrial processes. Methylchloroisothiazolinone is known by the registered tradename Kathon CG when used in combination with methylisothiazolinone.

Methylchloroisothiazolinone may be used in combination with other preservatives including ethylparaben, benzalkonium chloride, and bronopol.