Type: Compound
Vitamin: B2
Name: Riboflavin
RDA:1.5 mg
Importance- to Body:
Present in body as coenzymes FAD and FMN (flavin mononucleotide), both of which act as hydrogen acceptors in body; also is component of amino acid oxidases.
Distribution- in Body:
Named for its similarity to ribose sugar; has green-yellow fluorescence; quickly decomposed by UV, visible light, alkalis; body stores are carefully guarded; excess eliminated in urine.
Excess Effects:
None listed
Deficiency Effects:
Among the most common vitamin deficiencies.
Dermatitis; Cracking of lips at corners (Cheilosis); lips and tongue become purple-red and shiny; Ocular problems: Light Sensitivity, Blurred Vision
Food Sources:
Liver, Yeast, Egg White, Whole Grains, Meat, Poultry, Fish, Legumes, Milk
Environmental/Geographic Sources:
None listed
Supplemental information:
Chemical structure
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Clinical data | |
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Trade names | many |
Synonyms | vactochrome, lactoflavin, vitamin G |
AHFS/Drugs.com | Monograph |
Pregnancy category |
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Routes of administration |
by mouth, IM, IV |
ATC code | |
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Pharmacokinetic data | |
Excretion | Urine |
Identifiers | |
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CAS Number | |
PubChem CID | |
IUPHAR/BPS | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
E number | E101 (colours) |
ECHA InfoCard | 100.001.370 |
Chemical and physical data | |
Formula | C17H20N4O6 |
Molar mass | 376.37 g·mol−1 |
3D model (JSmol) | |
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Riboflavin, also known as vitamin B2, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to prevent and treat riboflavin deficiency and prevent migraines. It may be given by mouth or injection.
It is nearly always well tolerated. Normal doses are safe during pregnancy. Riboflavin is in the vitamin B group. It is required by the body for cellular respiration. Food sources include eggs, green vegetables, milk, and meat.
Riboflavin was discovered in 1920, isolated in 1933, and first made in 1935. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Riboflavin is available as a generic medication and over the counter. In the United States a month of supplements costs less than 25 USD. Some countries require its addition to grains.